KANSAS CITY, Mo. -- Things finally started to unravel for Seattle starter James Paxton in the eighth inning Thursday night.The full meltdown came when Steve Cishek entered in the ninth.The Mariners veteran closer gave up a leadoff single, plunked a batter and then served up a two-run double to Salvador Perez that allowed the Kansas City Royals to rally for a 4-3 victory to open their four-game series leading into the All-Star break.Not to mention ruin what should have been Paxtons big night.I dont know if you can be much more in control of the game to being on the wrong side of things in an inning and a half, Mariners manager Scott Servais said. Tough game to lose.Paxton only needed 78 pitches to cruise through eight innings, but he started to crack when Paulo Orlando hit a two-out double off him to get Kansas within 3-2. He retired Alex Gordon to escape the inning.Cishek (2-5) came on to close, and Whit Merrifields double, the hit-by-pitch of Kendrys Morales and the timely shot from Perez ultimately sent the Mariners to their 10th consecutive road defeat.How many times have we been through it? I mean, we fight. We keep fighting, said Danny Duffy, who kept the Royals in the game with 6 1/3 strong innings. Youre never out of the game with these boys.Brooks Pounders (1-0) earned his first career win with a scoreless inning of relief.Its a great moment in my life, the big reliever said. To walk away with a win in that game is just unbelievable. It says a lot about the team we have here.The win snapped a four-game skid for Kansas City. Seattle now has lost four in a row.You lose as a team, said the Mariners Robinson Cano. We dont want to blame anybody here.The Mariners built an early 2-0 lead not with a homer -- they entered the game tied for second in the majors with 128 of them -- but with old-fashioned small ball. Dae-Ho Lee scored from second on Dan Robertsons single in the second inning, and Robertson scored after a sacrifice bunt and sacrifice fly in the fifth.Nelson Cruz added a homer off Joakim Soria in the eighth.Those three runs seemed insurmountable the way Paxton was cruising along.He induced inning-ending double plays the first two innings, then another one in the third after back-to-back singles led it off. Ketel Marte then made a nice play ranging out from third base on Alex Gordons blooper into shallow left field to leave Brett Eibner on third base and end the inning.The worst throw Paxton made before the eighth wasnt to the mound but to first base, when Kendrys Morales chopped a grounder back to him the previous inning. Paxtons throw slipped and bounced halfway to the bag.With everything else going for him, it still beat Morales easily for the out.Pax pitched a good ballgame, Servais said. I felt very good about leaving him out there in the eighth inning. He certainly didnt have many pitches. His stuff was still good. Tough game to lose.STATS AND STREAKSMorales was 0 for 3 before getting hit by a pitch in the ninth, allowing him to extend his streak of reaching safely to 21 starts. ... The Mariners lost for the fourth time when leading after eight innings. ... Cruz homered for the seventh time in his last 14 games.ROTATION REMOVALThe Royals are sending RHP Chris Young to the bullpen and will start RHP Dillon Gee or LHP Brian Flynn in Sundays series finale. Young is 2-8 with a 6.90 ERA in 15 appearances, 13 of them starts. Hes also given up a league-leading 26 home runs despite pitching many of his games at spacious Kauffman Stadium.TRAINERS ROOMRoyals RHP Kris Medlen has been shut down after straining his shoulder during a rehab outing. Medlen was 1/3 with a 7.77 ERA in six starts before going on the disabled list in May with rotator cuff inflammation. He is going to be no-throw for a couple weeks, Royals manager Ned Yost said.UP NEXTRHP Yordano Ventura returns for Kansas City on Friday night after spraining his right ankle running the bases in his last start in Philadelphia. RHP Hisashi Iwakuma will oppose him for Seattle. Nike Vapormax Off White Australia .ca NFL Power Rankings, overtaking the Denver Broncos and remaining ahead of NFC competition San Francisco, Carolina and New Orleans. 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BLOOMINGTON, Ind. -- No. 13 Indiana will try to summon karma from its banner-hoisting past when hosting No. 3 North Carolina Wednesday night in a nationally televised ACC/Big Ten Challenge clash.The Hoosiers 1981 National Championship team, which defeated the Tar Heels in the title game, will be honored in a halftime ceremony. That Bob Knight squad had Isiah Thomas, Randy Wittman, Ray Tolbert and Landon Turner, among others.Problem is, those guys cant suit up against the latest Tar Heels (7-0), who are fresh off three wins by an average of 30.3 points at the Maui Invitational including a 71-56 finale over Wisconsin on Nov. 23. North Carolinas path to finishing last season as an NCAA Tournament runner-up included a 101-86 victory over Indiana in the Sweet Sixteen at Philadelphia.Im not going to go out and make my reservations for the Final Four, Tar Heels head coach Roy Williams said after the Wisconsin win. Ive never seen a national championship won the day before Thanksgiving. Its usually won that first Monday night in April.He would know. He celebrated national titles in 2005 and 2009.Indiana (4-1), ranked third before losing in overtime at Fort Wayne and dropping 10 spots, could be without its leading scorer in junior guard James Blackmon Jr., who is questionable with a left knee injury. The 20.5-point scorer, who also leads the team in 3-pointers with 15 out of 32 attempted (.469), missed Sundays 85-52 home rout of Mississippi Valley State.Blackmon has a lengthy history of significant knee injuries. He tore his left ACL in high school, meniscus in the same knee early in his college career and last year the right ACL prior to the Big Ten opener and missed the rest of the season.This afternoon, I go run, and I come through the weight room at the end before I go home to change, and there he is in the weight room doing his leg exercises, Indiana head coach Tom Crean said after Sundays win. Hes very, very diligent on getting himself ready. Hes been through a lot. Been through a lot before he even got here.So weve just got to make sure that were patiennt with him and help him get through that part of it, and hell know his body.ddddddddddddHes certainly got great support here, and hell get that. And well just see how the next few days go.While the Hoosiers average 88.6 points scored and have allowed 69.6 per game, the Tar Heels sport a 92.9-point average while allowing 65.6. Both teams shoot 3-pointers well -- Indiana has made 51 of 128 (.398) while North Carolina has hit 47 of 120 (.392).Five Tar Heels average in double digits, led by junior guard Joel Berry II at 17.1 points per game. Berry has a team-high 16 3-pointers and was just named ACC Player of the Week for a second time in this young season.Tar Heels junior forward/guard Justin Jackson averages 15.4 points with 11 3-pointers. Senior forward Isaiah Hicks checks in at 14.6 points and senior forward Kennedy Meeks averages 13.7 points and 10.7 rebounds per game.Were not perfect, Hicks said. We have to polish some things, especially on the offensive side. We need to move more and get a little better spacing. Sometimes we get caught standing there. And we always have to keep up our defensive intensity and effort.Indiana sophomore forward OG Anunoby bounced back from a flu-shortened scoreless game with a career-high 21 points Sunday to boost his scoring average to 11.8 points. The preseason All-American also grabs 6.2 rebounds per game.Hoosiers junior guard Robert Johnson averages 13.8 points and sophomore center Thomas Bryant averages 13.6 points and 8.2 rebounds.Crean, the 2016 Big Ten Coach of the Year, is matching wits against one of the all-time greats in Williams, a 29th-year Hall of Famer whose 790-209 record ranks eighth on the career win list. Crean has spent half of his 18 seasons at Indiana and has a 342-216 overall record.Indiana has an 8-6 series advantage including 2-1 in the ACC/Big Ten Challenge. Since 2011-12, Indiana has five wins against top-three opponents, which ties for second behind Dukes six. ' ' '